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[PMC free article: PMC4878518] [PubMed: 27140638] 263

This may be due to liver or kidney disease, or certain cancers and blood disorders: The aetiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis

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Spectrometric, biochemical, immunoblot, and immunohistochemical analyses were performed to assess the hepatic redox-active Fe 2+ intensity, metabolic function, anti-oxidative enzyme expression, and the pro-inflammatory cytokine levels