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To model natural-like GH pulses and IGF-1 activation in vitro and in vivo GH-axis studies

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187 This degradation results in DNA damage, potentially contributing to hepatocarcinogenesis, particularly in hepatocellular tumors with high NO synthase and low GSNOR levels

Additionally, experiments that induced iron overload in the hippocampus and prefrontal cortex of male rats led to the development of schizophrenia-associated behaviors (37), suggesting that both an excess and a deficiency of iron could foster changes in the brain associated with schizophrenia

10.3389/fnut.2023.1115069 105