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Congestive heart failure (CHF)

Grisolia S, Cohen PP

Acute, regulated ROS generation is indispensable for effector activation, whereas chronic, unmitigated oxidative stress drives exhaustion of cytotoxic T cells while simultaneously reinforcing Treg-mediated immune suppression

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It provides an alternative nutrient source of metabolites, such as amino acids and other essential nutrients, that support mitochondrial function and protein synthesis in macrophages more effectively than live bacteria