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Again, patients with metastatic colorectal carcinoma to the liver have a higher rate of response to bevacizumab plus chemotherapy when they have angiogenic metastases, while the poor responders have mostly non angiogenic secondaries [30]

Biomaterials 154 , 6073 (2018)

Interestingly, stimulation of signal transducer and activator of transcription 3 (STAT3) in astrocytes could reverse the mitochondrial impairment (Engin and Engin, 2021) and thus may be a novel candidate for the pharmacological treatment of PTSD