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doi: 10.1186/s12974-018-1308-0 183 LiRTangHBurnsJCHopkinsBTLe CozCZhangBet al

In conclusion, among the four studied compounds Lapatinib could be a promising scaffold for developing effective leads capable of activating GPx4 and assist in the treatment of MS

Although no studies examining the chemical mechanism have been published, structural similarity between the plant and yeast GCL suggests a shared reaction (Biterova and Barycki, 2009)