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A mitochondria-targeted covalent organic framework (COF) prodrug that is selectively activated by high intramitochondrial GSH levels was shown to trigger catalase collapse within the organelle, thereby amplifying local chemodynamic therapy (CDT) through enhanced ROS accumulation and mitochondrial dysfunction

At present, fMRI-based NFT is also used in the treatment of mental illness and emotional regulation (Pavla et al., 2019)

Supplemental Material This article contains the following supplemental material online at Supplemental Figure 1

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