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It is believed that Schisandra sphenanthera extract facilitates the nuclear accumulation of the transcription factor NRF2 to mitigate cisplatin-induced nephrotoxicity, which is important for therapeutic approaches to AKI [122]

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Development and grouping of DFU rat models Sixty SD rats were acclimated for one week before being randomly assigned to one of the following groups: the control group, which continued on a normal diet, or one of the experimental groups: the model group, positive drug group (rhEGF), and high (DP-H), medium (DP-M), and low (DP-L) dose DP groups

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This is why vitamin B12 is generally considered safe even at very high doses

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Two high-risk APOL1 alleles (G1G1, G2G2, or G1G2) raise kidney disease risk significantly while inheriting one low-risk allele (G0G1 and G0G2) does not increase the risk of CKD

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