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It inhibits prostaglandin synthesis by modulating cyclooxygenase (COX) enzyme activityespecially COX-2 and a central COX-3 variantresulting in analgesic and antipyretic effects

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322(Pt 1), 103109 [DOI] [PMC free article] [PubMed] [Google Scholar] Sharma R., Singhal S

For severe or acute joint injuries, injectable forms are often preferred in research for their higher bioavailability

is a scientific advisory board member for AbbVie, Allergan, Amgen, AstraZeneca, Avaxia Biologics Inc., Boehringer-Ingelheim, Bristol-Myers Squibb, Celgene, Elan, Biogen, Ferring, Genentech-Roche, JanssenJohnson & Johnson, Merck, Millennium, Nestl, Novo Nordisk, Novartis, Pfizer, Prometheus, Protagonist, Receptos, Salix, Sigmoid Pharma, Takeda, Teva, TiGenix, Tillotts Pharma and UCB Pharma