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Though this in of itself is not conclusive evidence of anything, it has led to an age-related epigenetic drift theory where abnormalities in epigenetic machinery and exposure to certain environmental factors which occur earlier in life lead to aberrant DNA methylation patterns far later, contributing to sporadic Alzheimer's Disease predisposition

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Dihexa acts primarily through hepatocyte growth factor (HGF) signaling by potentiating HGF/c-Met receptor interaction