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The threshold concentration for tubular reabsorption (above which the fractional reabsorption begins to decline) is about 40-60 umol/L, which is similar to the endogenous plasma L-carnitine level

Y.WangC

However, more work is certainly needed to further understand the cause-and-effect relationship of uric acid on mammalian health [63], as elevated uric acid, under pathogenic circumstances, may also indicate increased oxidative stress [64]