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10.1007/s12264-018-0269-8 151 WhittleB

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Mechanism of action: 1) Activation of amylin receptors (AMY1, AMY2, AMY3 heterodimers of calcitonin receptor with RAMP1/2/3) in area postrema and NTS appetite suppression and enhanced satiation

doi: 10.1016/j.clinbiochem.2010.02.005 80 RamliNSFMat JunitSLeongNKRazaliN

Other data supporting ROS participation in this process are that N-acetylcysteine restores total myocardial glutathione, lowers oxidative stress, and reduces myocyte hypertrophy and fibrosis in aortic stenosis rats [153]