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Treatment with AMSH, OTUB1, and Cezanne all reduced, to varying extents, high molecular weight IL-1 ubiquitylation, whereas OTULIN treatment to remove linear ubiquitin chains had no impact

As a result of ferroptosis, CRT is translocated onto tumor cells, where it can induce a robust immune response against the tumor (77)

Among chronic liver diseases, MASLD increased over time, while viral hepatitis declined