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Description

Among the tested alkaloids, speciogynine induced the strongest LLR effect with an ED 50 value of 23 mol/kg, followed by paynantheine (26 mol/kg) and mitragynine (62 mol/kg)

P gst-4 ::GFP presented a significant induction by FA in control worms, further exacerbated by silencing adh-5

Life Sci 1990

Molecular dynamics simulations Molecular dynamics simulations have been performed using the AMBER ff19SB force field 57 and the solvent molecules were represented as OPC water molecules 58