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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.da Silva T., Mills K., Brown B.T., Herbert R.D., Maher C.G., Hancock M.J

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Muzumdar RH, et al

"I had my serotonin level tested before starting a methylfolate and active B12 regimen

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Conventional DMARDs (e.g., methotrexate, leflunomide, sulfasalazine): Methotrexate slows joint damage and suppresses inflammation but causes hepatic toxicity and bone marrow suppression, leading to 30% treatment discontinuation within one year (8)