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There were similar rates of mild adverse events (e.g., nausea, restlessness, insomnia, irritability) across groups in trials of cytisine based on our initial overview.22 However, an updated Cochrane review on cytisine42 suggested there may be a small increase in adverse events, which could constitute a small harm (4 RCTs, n = 4052

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More importantly, the more consistent your stick is in both diameter and packing, the better you will enjoy the flavors of all of your favorite rolling tobaccos