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SQSTM1 and its MAP1LC3B-binding domain induce forced mitophagy to degrade mitochondrial carryover during mitochondrial replacement therapy

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Future research could explore the molecular mechanisms underlying the effects of specific amino acids on stress responses, the long-term effects of dietary amino acid manipulation, and the potential for genetic approaches to enhance amino acid utilization

In accordance with this, associations between chronological age and a higher ROS production rate of mitochondria in brain cells were demonstrated in rodents (Navarro and Boveris, 2004