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doi: 10.1038/s41591-022-01934-9 159 GaviglioAMSkinnerMWLouLJFinkelRSAugustineEFGoldenbergAJ

Among this class of drugs, though it is subject to first pass metabolism, mebendazole has relatively high oral bioavailability, allowing for oral rather than injectable dosing

The researchers utilized the Achilles functional index (AFI), myeloperoxidase activity, histological inflammatory cell influx, and vascular index as potential markers