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Unlike sepsis, where treatments are primarily directed against LPS-induced inflammatory responses (e.g., anti-endotoxin antibodies), SAP-induced glycocalyx damage is predominantly driven by pancreatic enzyme activation (e.g., trypsin) and intestinal endotoxin release

Wahab S, Anwar AI, Zainuddin AN, Hutabarat EN, Anwar AA, Kurniadi I

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When taken internally, GHK-Cu may have more severe side effects, from skin irritation to headaches and nausea