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After digestion, the samples were centrifuged at 12,000 g for 10 min at 4 C, and the supernatant was collected

(4610:) plasma carboxypeptidase B2 isoform b [Homo sapiens]

The 29 MF were predicted, among which Small molecule binding (GO:0036094) was predicted with an FDR of 5.11E-07, whereas it was found to modulate 19 proteins (CDC34, ATP5F1B, NTRK2, HMGCR, MAP2K1, PRKDC, IDH2, PDE2A, MAP4K4, FOXO1, NTRK3, HSD11B1, ADORA1, PRKAA2, SIRT3, CDK1, NTRK1, SOD2, IGF1R)

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140 Aspirin has also been shown to induce non-apoptotic cell death in human melanoma cells by disrupting the mitochondrial network and increasing mitochondrial Ca + levels and reactive oxygen species (ROS)