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Improving radiotherapy in cancer treatment: promises and challenges

Journal of Molecular Endocrinology, vol

We also showed that irisin mitigates mitochondrial damage by downregulating lactate metabolism via the SIRT1 pathway

The antioxidant property of Sp was however, found to be insensitive to depletion of glutathione by BSO, which generally causes loss of cellular antioxidant function and higher ROS (Fig