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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

doi: 10.1016/S0022-510X(03)00004-2 115 Machado-SantosJSajiETroscherARPaunovicMLiblauRGabrielyGet al

The UniProtKB sequence databases of yeast or human were searched for proteins harboring the short linear motif [R/K]-P-W-[E/Q] using the webtool ScanProsite ( Hits were then compared with proteins listed as yeast and human PEX7 interactors in the BioGRID database

Show Notes Rehabilitation of Athletic Low Back Pain Online Course Chronic Lower Back Pain in Weight Lifters: Epidemiology, Evaluation, and Management Transcript Mike Reinold: Welcome back, everybody, to the latest episode of the Ask Mike Reinold Show

At the molecular mechanism level, critical questions remain unanswered: the specific molecular interaction networks underlying NTFs-mediated mitochondrial regulation (e.g., the full spectrum of PGC-1 post-translational modifications, the selective recognition mechanism of NTFs-induced mitophagy) have not been fully elucidated, and heterogeneous responses at the single-cell level require further investigation