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Our body dont produce B12 (except in gut flora, which humans cannot absorb), so we must obtain it from B12-rich foods, particularly animal-based products like meat, eggs, and dairy

In fact, many non-deficient people do this because they believe it provides a boost in energy

PMID 6789105

Thus, xCT inhibitors enhance mitochondrial respiration and increase ROS production to promote ferroptosis, which may be a potential therapeutic strategy in cancer cells exhibiting metabolic reprogramming from glycolysis to OXPHOS

For people with methylation concerns (including those with MTHFR gene variants), long-term daily supplementation, or anyone who wants a more direct pathway to usable B12, methylcobalamin is generally the stronger choice