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The significance of this finding for the clinical management of these patients is also becoming clearer

Lysine fortification reduces anxiety and lessens stress in family members in economically weak communities in northwest Syria

Another hypothetic role of bromelain is in the inflammation caused by advanced glycation end-products (AGEs)

During ER stress, stimulator of interferon genes (STING), a transmembrane protein predominantly located in the ER, responds to stress signals and promotes inflammasome activation, such as NLRP3, via the STING/ TANK-binding kinase 1 (TBK1) pathway, leading to tissue inflammation (61)