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The clinical efficacy of PRP is intrinsically linked to the concentration of platelets and the subsequent release of a plethora of growth factors, notably VEGF, platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-1 and TGF-2), epithelial growth factor (EGF), and insulin-like growth factor (IGF) [27,28]

Reducing carbohydrate intake through KD may have a positive effect on this

Antioxidants are substances that inhibit the oxidation of other molecules

To minimize the risk of bone damage or digit tip regeneration, toenails were trimmed one day prior to drug application and the initial CT scan