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In addition, the plasmalemmal presence of TRPM7 stabilizes the plasma membrane expression of LRRC8A protein through the protein-protein interaction between LRRC8A and the C -terminal -kinase domain of TRPM7

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Doses exceeding approximately 100 mg of oral morphine equivalent may be more likely to trigger the onset of OPIAD, compared with lower opioid doses [73], although this finding has not been confirmed by other researchers [56, 65]

Reduced anxiety-like behavior and central neurochemical change in germ-free mice