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optionally, identifying the subject as being a responder based on age and/or baseline GSH levels

doi: 10.3389/fcell.2021.791880 69

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As the drug rapidly elevates systemic blood pressure, it activates stretch receptors in the carotid sinus and aortic arch

Moreover, recent studies show that p53 induces the expression of the alpha (II) collagen prolyl-4-hydroxylase [alpha (II)PH], which results in the production of anti-angiogenic collagen type 4 and 18 fragments [25]