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Food and Drug Administration Updated 503A bulk drug substances list (Category 2 revision, effective April 22, 2026)

doi: 10.1172/JCI8124 41 SoumelisVRechePAKanzlerHYuanWEdwardGHomeyBet al

Protein tags are proteins or peptide sequences that are genetically fused to a target protein to enable the detection and purification of the target protein

Stevenson S, Thornton J

Key takeaways NMN is a naturally occurring molecule that the body converts into NAD, which is essential for energy production, DNA repair, and overall cellular function