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Massachusetts General Hospital, Boston, Massachusetts (Matta, Stern)

Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy

Oxidatively truncated phospholipids are required agents of tumor necrosis factor alpha (TNFalpha)-induced apoptosis

It also promotes skin health by reducing the damage caused by oxidative stress

These results corroborate our previous findings ( Ferroptosis, a form of iron-dependent cell death characterized by oxidative lipid damage and impaired antioxidant capacity, has emerged as a key player in cisplatin nephrotoxicity ( , specifically its subunit xCT, impairs cystine uptake and GSH synthesis, weakening the antioxidant capacity of GPX4, the primary enzyme responsible for reducing lipid hydroperoxides