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Description

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

Demonstrates persistent cognitive benefits even after treatment cessation, suggesting true structural neurological improvements rather than temporary stimulation, supporting long-term brain health

An increased interferon gene signature was observed in patients with early RA (eRA), which predicted a poor response to the initial therapies in the first 6 months after diagnosis (8)