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Moving forward, the field will need to balance technological ambition with responsible innovation

*Correspondence: Bernard Crespi, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Affinity-based chemistries such as biotin-streptavidin binding and carbodiimide coupling are also used

New synapses form, dendritic arbors expand, receptor clusters reorganize