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Description

The Jackson Laboratory)

Biomedical applications of cyclodextrin based polyrotaxanes

This interview has been lightly edited and condensed for clarity and length

We hypothesized that the metabolic perturbation caused by 3BP, in particular its effects on glycolysis, redox homeostasis, and nucleotide synthesis, could potentiate the cytotoxic effects of ionizing radiation with selectivity toward cells expressing MCT1