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It has demonstrated low skin irritability when applied topically, both with and without microneedle-assisted delivery

Herein, quantitative analysis of P

Based on this, specific markers related to ROS-induced modifications can be defined and summarized in Figure 1

Furthermore, it is abundant in vitamins C, A, E, D, B1, B2, and B12, trace minerals, and antibiotics (101, 102)

It is a frequent and life-threatening complication, particularly in Intensive Care Units (ICU), where it commonly arises in post-operative patients (24), hyperoxemia induced by mechanical ventilation or extracorporeal membrane oxygenation (25), systemic inflammation (26), and the metabolic effects of critical illness (27, 28), all of which may contribute to neuronal damage and cognitive dysfunction