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Ewers | Ambrose, Undaunted Courage, reviewed by Harry W

The accumulation of oxidized lipids, such as prostaglandin E2 (PGE2), fatty acid transport protein 2 (FATP2), and arachidonic acid, also contributes to MDSC-mediated immune suppression through oxidative stress [460]

However, it is not considered an essential nutrient because the body can make it from the amino acids lysine and methionine

Consistent with the study, in reference [169], serum PON activity and total antioxidant capacity were significantly lower in patients with the -thalassemia trait patients, MDA and carotid artery intima-media thickness were significantly higher in -thalassemia trait