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This occurs because alcohol confuses osmoreceptors in the hypothalamus, which relay osmotic pressure information to the posterior pituitary, the site of antidiuretic hormone release

Their strategy worked

If the shot is given directly into a vein, a lot of the Vitamin B12 might end up being lost when someone pees

This same commenter suggested that CMS should consider in the interim, implementing waivers for individual cases where an audio-only telecommunications evaluation of the patient is the only means that a patient can access services, or where there is an insufficient supply of OTP providers in the area to prescribe or dispense methadone

It's largely anecdotal, based on the logical (but not necessarily scientifically validated) idea that putting the peptide closer to the site of injury will make it work better or faster