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Description

Introduction Primary carnitine deficiency (PCD, MIM:212140) is an autosomal recessive disorder of carnitine transportation

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The specific transporter involved with SPCD is OCTN2 [5] , coded for by the SLC22A5 gene located on chromosome 5

L-Carnitina este, de asemenea, cunoscut pentru efectele sale pozitive asupra sntii inimii

A 24 h fasting period of WT or ob/ob mice, upregulated PPAR and PPAR-target genes related to mitochondrial (medium- and long-chain acyl-CoA dehydrogenases), peroxisomal (acyl-CoA oxidase (ACOX) 1 and enoyl-CoA hydratase), and cytochrome-mediated (CYP4A1 and CYP4A3) FAO [85]