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Hai Wen (Shanghai Changzheng Hospital, Second Military Medical University) for his assistance in the design of this case report

It acts on adipocytes to enhance the hydrolysis of stored triglycerides without globally activating growth hormone cascades

Intramuscular (IM) hydroxocobalamin is the recommended first-line treatment for pernicious anaemia in the UK, as advised by NICE and the British Society for Haematology

On the other hand, double Ghr ko/ Igf1 ko resulted in further postnatal growth retardation relative to Igf1 ko mice completely obstructing further weight gain after postnatal day 15 and supporting previous studies suggesting that progenitor cells in the growth plate require direct GH actions (24)

Loading regimens involve 1 mg three times weekly for two weeks, or alternate-day dosing if neurological symptoms are present