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Collectively, these findings suggest that exercise training exerts anti-oxidative effects through regulating the activity of enzymes, nuclear factors, and oxygen-free radicals

A review published in Gynecological Endocrinology by Calleja-Agius and Brincat (2012) described a strong correlation between skin collagen loss and oestrogen deficiency, noting that oestrogen replacement after menopause increased collagen content, dermal thickness and elasticity (PMID: 21970508)

J Cell Biol 218(8):25832599 Chen Y, Azad MB, Gibson SB (2009) Superoxide is the major reactive oxygen species regulating autophagy

Range of motion expands

Future studies utilizing conditional knockout models and endogenous tagging approaches will be valuable in further validating these findings