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Tirzepatide as a Dual GIP/GLP-1 Receptor Agonist Tirzepatide is unique because it activates two metabolic hormone pathways at once: GLP-1 (glucagon-like peptide-1): Helps regulate appetite, slows gastric emptying, improves insulin secretion, and reduces post-meal blood sugar spikes

Exposure also resulted in eryptosis induction, probably due to the prooxidative effect of lead (2.4-fold higher levels of thiobarbituric acid reactive substances (TBARS) and 32.8% lower GSH/GSSG ratio)

VijayvargiyaPCamilleriMCarlsonPNairANordSLRyksMet al

For electrophysiological recording, cells were seeded onto 12 mm diameter poly-D-lysine coated glass coverslips at a density of in 24-well plates and grown for 48 hours before experiments

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