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Even "non-sedating" second-generation antihistamines can cause fatigue, cognitive impairment, and what many describe as "brain fog." 2 Research has shown that chronic use of first-generation antihistamines is associated with concerning effects, including memory problems

doi: 10.1016/j.mcn.2004.07.003 77 AlbiniAFerriniSBenelliRSforziniSGiunciuglioDAluigiMGet al

10 Conclusion and perspectives AD was discovered over a century ago, yet the exact disease-causing process is still not well understood, even though amyloid-beta deposits and neurofibrillary tangles in the brain are the most common signs of Alzheimers disease pathology

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