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confirmed increased small nerve fibre abundance in both skin and cornea Sarcoidosis-associated small fibre neuropathy Phase 2 RCT confirmed ARA-290 produced relief of neuropathy-related symptoms in sarcoidosis patients with moderate-to-severe neuropathic pain, with approximately 50% response rate versus placebo

Sources Footnotes Yazbek PM, Ovanessian V, Martin RL, Fukuda TY

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Its demonstrated cartilage regeneration effects in preclinical models, combined with favorable safety characteristics, position it as a compound worthy of further clinical investigation