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CrossRef Fluorescence imaging for photodynamic therapy of non-melanoma skin malignancies A retrospective clinical study Sergey Gamayunov, Ilya Turchin, Ilya Fiks, Kseniya Korchagina, Mikhail Kleshnin, Natalya Shakhova Photonics & Lasers in Medicine.2016

It is the case for xCELLigence cell index which is a highly sensitive method, allowing to detect and quantify cell adhesion modifications in shorter times (few minutes) than fluorescence imaging or cytometry in TRITC-phallodin labeled cells (2.5H)

However, current research faces two fundamental limitations: (1) The studies of structure-activity relationship predominantly remain at the level of apparent bioactivity, lacking molecular-level mechanistic evidence