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Structurally, zinc stabilizes the tertiary and quaternary architectures of proteins, including zinc-finger domains in transcription factors, and facilitates proteinprotein, protein-DNA/RNA, and protein-lipid interactions (69)

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Minias, A., Minias, P., Czubat, B

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However, in the cell types that possess the specific peptide receptor, its activation should lead to internalization of the ligand-nuclear hormone receptor complex