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Neurochem Res 32(11):19902001

Parkinsons disease (PD) is one of the most common neurological disorders caused by the death of dopamine-secreting neurons in the brain due to aggregation of synuclein protein inside it

5-amino-1MQ, an analogue from our initial series of NNMT inhibitors with low IC50 value (IC50=1 M), and high cell membrane permeability (Table 5), produced the greatest reduction of intracellular 1-MNA levels at a concentration of 10 M among tested inhibitors

They do not permanently shrink or restore the dilated veins

Still, I'd recommend using with caution, i.e., don't leave your iPad attached to your MacBook Pro all the time