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Some studies have suggested that GH and IGF-1 can increase muscle mass and reduce body fat, but its mostly been shown in animals and people with low levels of GH, like the elderly or those with a medical issue causing a deficiency

For example, a two-photon imaging study of a ketamine and stress-induced mouse model of bipolar disorder, demonstrated that brain Ca 2+ activity measured in situ was reduced in mice displaying both manic and depressive-like behaviours [26]

Yue, R., Zhou, B

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