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Weeks 2 to 4: Stronger responders notice physical changes, including better range of motion, fewer flare-ups, and the ability to handle more physical load

doi: 10.1002/cncr.31213 30 D'CruzAKVaishRKapreNDandekarMGuptaSHawaldarRet al

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Buffers (Table 2) are added to parenteral formulations to adjust the pH [33, 36, 37] with the aim of optimizing solubility and stability, and are typically used in the 10100 mM range [33]