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Dual targeting to overcome current challenges in multiple myeloma CAR T-cell treatment

Heme interaction of the intrinsically disordered N-terminal peptide segment of human cystathionine-beta-synthase

FIGURE 10 Oxidative stress, associated with high dose MTX, triggers a systemic inflammatory response where proinflammatory cytokines further contribute to tissue damage (Kalantar et al., 2019a