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The Mediterranean diet, which includes abundant fruits, vegetables, olive oil and whole grains, is loaded with dietary fiber, polyphenols, and unsaturated fatty acids, which improve beneficial bacteria growth, such as butyrate producers, including Clostridium leptum and Eubacterium rectale , and reduce the growth of pro-inflammatory bacteria such as Firmicutes

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It regenerates other oxidized antioxidants like vitamin C and vitamin E, is involved in the repair of peroxidized lipids and in the maintenance of sulfhydryl moieties of proteins in the reduced form

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Several researchers have evaluated the potential of these phytocompounds (Table 3) and underlying anti ulcerative mechanisms using various animal models that have been summarized below: 6.4.1 Nitrogen containing compounds Nitrogen containing secondary metabolites, especially derived from medicinal plants exhibits a potent anti-inflammatory and immune regulating properties against UC [123]