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Klotho Peptides# Evidence Level: Primate data | FDA Status: Not approved Klotho peptides are derived from alpha-klotho, a transmembrane protein whose loss causes accelerated aging and whose overexpression extends lifespan in mice

Emergency management includes IV fluid support, electrolyte rebalancing, antiemetic medications, and blood glucose monitoring

In the absence of a unified conceptual framework, distinctions between neuroprotection, symptomatic treatment, and disease modification often become obscured, risking the conflation of mechanistic plausibility with demonstrable clinical benefit

Applying ice to the treated area in the first few hours may also help reduce swelling, if recommended by your provider

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