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Philpott, [email protected] This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

271,272 In addition, treatment with mannitol can be considered in the early stages of SCI if local edema or elevated pressure is present

This inspired us to hypothesize that inhibition of cholesterol biosynthesis branch of the mevalonate pathway may result in a concomitant shift of the metabolic flux to CoQ10 synthesis