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Complementing experimental advancements, bioinformatics and computational tools play a critical role in analyzing and interpreting vast epigenomic datasets

Histone Kla can affect gene expression in tumors and immunological cells, thereby promoting malignancy and immunosuppression

Fish Physiol Biochem 30:189199 Huang W, Cao L, Liu J, Lin L, Dou S (2010) Short-term mercury exposure affecting the development and antioxidant biomarkers of Japanese flounder embryos and larvae

This is achieved by upregulating Bax and downregulating Bcl-2 [70, 71]

Common genetic variants alone do not account for the variability in treatment response, positioning DNA methylation as a promising area for exploring the underlying pathophysiology and therapeutic outcomes of schizophrenia (van Os and Kapur, 2009)